Flavor masking and palatability solutions for oral dosage forms. Built around the active, excipient system, and compliance requirements, not just taste.
These are the formulation problems that come up in every pharmaceutical flavor project.
Most active pharmaceutical ingredients are bitter. This is related to the molecular structures that make them pharmacologically active. Masking requires understanding which bitter receptor subtypes the specific API activates, then using systems that address those receptors. A general sweet masking flavor does not solve API bitterness.
Sorbitol, mannitol, xylitol, and sucralose each have distinct taste backgrounds that interact with the masking system. A flavor built to mask the API has to account for the full excipient stack. Changes to excipient levels late in development can require re-masking work.
Liquid oral formulations require flavor systems that are stable over shelf life without contributing to pH drift, compatibility issues with preservatives, or unwanted interaction with the API suspension.
Flavor regulatory status (GRAS, QS, FEMA), declaration requirements, and allergen statements are documentation requirements in pharmaceutical formulation work. The flavor system has to be built from qualified ingredients with documentation available from the start.
Recognizable sweet-tart berry character for confectionery, beverages, dairy, nutraceuticals, and masking work.
Sweet cherry built specifically for pharmaceutical liquid dosage forms. Formulated to complement typical excipient systems and hold through the dosing experience without turning artificial.
Grape-based palatability flavor for pharmaceutical liquid suspensions. Addresses active bitterness while complementing standard pharma excipient backgrounds. Confirm excipient compatibility.
Programs relevant to pharmaceutical applications.
Yes. Our approach targets the specific bitter receptor subtypes being activated by the API, which is more effective than simply adding sweetness. Masking systems that address the receptor require less sweetener load.
Yes. We provide GRAS status, FEMA numbers, allergen statements, and other documentation as part of standard pharmaceutical flavor work.
Liquid suspensions, chewable tablets, and lozenges. Pediatric palatability development requires specific sweetness profiles and mouthfeel characteristics.
API name or off-note profile, dosage form, excipient system, dose volume, target age group if pediatric, and palatability goals.
We evaluate bitterness masking effectiveness, sweetness balance, mouthfeel, and aftertaste character systematically. For clinical palatability work, we can structure samples around your evaluation criteria.
Include API name or off-note profile, dosage form (liquid, chewable, lozenge), excipient system, dose volume, and target age group if pediatric. Samples typically ship in 3-5 business days.
